Phospho.ELM Result

a database of S/T/Y phosphorylation sites

Statistics:
	Instances	42.914
	Kinases	299
	References	3.657
	Sequences	11.224
	Substrates	8.698

PDGF-R alpha (Receptor tyrosine kinase)

Seq-ID:

P16234 [Homo sapiens]

Download:

Interaction Network(s):

STRING

NetworKIN

External Source(s):

Phosida

MINT Interaction(s):

-

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
platelet-derived growth factor alpha-receptor activity, vascular endothelial growth factor receptor activity, platelet-derived growth factor binding, protein homodimerization activity, platelet-derived growth factor receptor binding, ATP binding	integral to plasma membrane	positive regulation of DNA replication, positive regulation of fibroblast proliferation, cell activation, positive regulation of cell migration, protein amino acid autophosphorylation, peptidyl-tyrosine phosphorylation

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
Y	572	IESISPDGHEYIYVDPMQLPY	-	11818394	LTP	1.00		Src SH2	-	0.13	-	medium
Y	574	SISPDGHEYIYVDPMQLPYDS	-	11818394	LTP	1.00		Src SH2	-	0.15	-	medium
Y	720	LNPADESTRSYVILSFENNGD	-	11818394	LTP	0.21		PTPN11 SH2; SHB SH2	TyrKc	0.29	-	medium
Y	731	VILSFENNGDYMDMKQADTTQ	-	11818394	LTP	1.00		PIK3R1 SH2	TyrKc	0.29	-	medium
Y	742	MDMKQADTTQYVPMLERKEVS	-	11818394	LTP	1.00		PIK3R1 SH2	TyrKc	0.39	-	medium
Y	754	PMLERKEVSKYSDIQRSLYDR	PDGFR_alpha	7523122	LTP	0.27		PTPN11 SH2	TyrKc	0.29	-	medium
Y	762	SKYSDIQRSLYDRPASYKKKS	PDGFR_alpha	9546424	LTP	1.00		CRKL SH2; CRK SH2	TyrKc	0.29	-	medium
Y	762	SKYSDIQRSLYDRPASYKKKS	-	18083107	HTP	1.00		CRKL SH2; CRK SH2	TyrKc	0.29	-	medium
S	767	IQRSLYDRPASYKKKSMLDSE	-	8617789	LTP	0.17		-	TyrKc	0.31	-	medium
Y	768	QRSLYDRPASYKKKSMLDSEV	-	16497976	HTP	0.11		-	TyrKc	0.31	-	medium
Y	768	QRSLYDRPASYKKKSMLDSEV	-	18083107	HTP	0.11		-	TyrKc	0.31	-	medium
Y	849	LARDIMHDSNYVSKGSTFLPV	-	18083107	HTP	1.00		-	TyrKc	0.12	-	medium
Y	988	ARMRVDSDNAYIGVTYKNEED	PDGFR_alpha	7535778	LTP	0.12		PLCG1 SH2	-	0.41	-	medium
Y	1018	DEQRLSADSGYIIPLPDIDPV	PDGFR_alpha	7535778	LTP	1.00		PLCG1 SH2	-	0.49	-	medium
Y	1018	DEQRLSADSGYIIPLPDIDPV	-	18083107	HTP	1.00		PLCG1 SH2	-	0.49	-	medium